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Figure 6 | BMC Complementary and Alternative Medicine

Figure 6

From: Muscadine grape skin extract reverts snail-mediated epithelial mesenchymal transition via superoxide species in human prostate cancer cells

Figure 6

Pathway by which MSKE antagonizes Snail-mediated EMT in prostate cancer cells. Snail induces EMT via superoxide production which is characterized by decreased E-cadherin expression, increased vimentin expression and increased cell migration. MSKE antagonizes Snail-mediated EMT by inhibiting Snail expression possibly via inhibition of Stat-3 activity and superoxide production.

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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