Figure 2
From: Role of berberine in anti-bacterial as a high-affinity LPS antagonist binding to TLR4/MD-2 receptor
Therapeutic effect of berberine on LPS-challenged Balb/c mice. n = 10 in each group. Each mouse was injected with 2 EU/ml bacterial endotoxin (0.5 ml for each). The LPS-challenged mice was administered intragastrically with distilled water (0.01 ml/g) or berberine at doses of 0.20, 0.16 or 0.13 g/kg. The survival was assessed once an hour throughout the experiment. The average death time of each group was calculated within Mean ± SD adopted. P < 0.05 vs control.