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Table 1 Values of physical parameters of four curcuminoids examined in this study

From: Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer’s disease Drosophila models

Compound MWa logP b MRc Sourced
Curcumin 368 2.92 104 S-A
Demethoxycurcumin 338 3.08 98.78 S-A
Bisdemethoxycurcumin 308 3.32 92.10 S-A
Tetrahydrocurcumin 372 2.73 100.63 S-A
  1. aMolecular weight.
  2. bHydrophobic parameter expressed as the log of the octanol/water partition coefficient.
  3. cParameter for steric effects as described using molecular refraction.
  4. dPurchased from Sigma-Aldrich (St. Louis, MO).