Grailsine-Al-glycoside triggered significant
apoptosis in A549, MCF-7, and Hela
cells. Cells treated with different
concentration of Grailsine-Al-glycoside for 36 hrs
before stained with propidium iodide and underwent
flow cytometry analysis. The apoptotic cells were
measured by sub-G1 population.
Grailsine-Al-glycoside induced over 2 fold
increase of apoptosis in A549 (A), Hela (B), and MCF-7 (D) cells but moderate
increase in HepG2 cells (C).