Skip to main content

Table 4 Rectal temperature, weight and packed cell volume of infected animals treated with crude extract of Croton macrostachys in the Rane’s test

From: In vivo antimalarial activity of the crude leaf extract and solvent fractions of Croton macrostachyus Hocsht. (Euphorbiaceae) against Plasmodium berghei in mice

Animal group T0 T4 % change W0 W4 % change PCV0 PCV4 % change
CON 37.4±0.14 36.6±0.05 −2.2 26.2±0.21 22.1±0.43 −7.7 54±0.31 53±0.21 −4.9
CM200 37.3±0.08 37.2±0.08 −0.2a2 26.3±0.11 25±0.16 −3.1a1 53±0.31 52±0.40 −1.9
CM400 37.4±0.09 37.4±0.04 0.0a3 26.4±0.11 26.3±0.05 −1.1a3 52.5±0.43 53±0.22 0.9
CM600 37.3±0.09 37.4±0.03 0.2a3 26.6±0.06 25.9±0.05 −1.8a2 52±0.31 53±0.44 1.9
CQ25 37.4±0.18 37.3±0.13 −0.2a2 26.5±0.04 25.9±0.04 −2.3a2 52.5±0.42 53±0.21 2.4
  1. Data are expressed as mean ± SEM; n = 6; a,compared to controls, 1p<0.05, 2p< 0.01, 3p< 0.001; CM, crude extract of Croton macrostachys; W, weight; T, temperature; PCV, packed cell volume; 0 refers at day 0 and 4 to day 4. Numbers refer to dose in mg/kg.