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Table 3 Effect of Paederia foetida Linn. on antioxidant marker in STZ-induced diabetic rats

From: Paederia foetida Linn. leaf extract: an antihyperlipidemic, antihyperglycaemic and antioxidant activity

S. No. Biochemical parameter Normal control Normal control + PF (500 mg/kg) STZ-Diabetic control STZ diabetes + PF I (100 mg/kg) STZ diabetes + PF II (250 mg/kg) STZ diabetes + PF III (500 mg/kg) STZ diabetes + Glibenclamide (10 mg/kg)
1 SOD (U/mg of protein) 7.8 ± 0.374 7.6 ± 0.245 2.2 ± .374a 4.2 ± 0.374b 5.2 ± 0.374b 7 ± 0.316b 6.6 ± 0.245b
2 CAT (U/mg of protein) 72 ± 1.612 70.6 ± 1.72 38 ± 1.732a 45.8 ± 1.068b 53.8 ± 1.158b 68 ± 1b 65.4 ± 1.077b
3 GPx (nmole/mg of protein) 32.8 ± 1.02 32.6 ± 1.208 13.2 ± 0.374a 19 ± 0.707b 24.6 ± 0.509b 31 ± 0.458b 29.6 ± 0.927b
4 MDA (nmole/mg of protein) 0.2 ± 0.011 0.21 ± 0.007 0.54 ± 0.013a 0.39 ± 0.009b 0.32 ± 0.005b 0.25 ± 0.005b 0.26 ± 0.003b
  1. Values are given as mean ± S.E.M. of six rats in each group. a(P <0.01) compared with the corresponding value for normal control animals (group I); b(P <0.01) compared with the corresponding value for diabetic control animals (group III); ns-non significant.