Paederia Foetida Linn. leaves extract effect on heart histopathology in normal and STZ induced diabetic rats. (A) Normal control: Did not display any changes (B) Diabetic control: Histopathology of diabetic control group rat display increased interstitial space and distort the intercalated disc (yellow arrow) (C) PF I (100 mg/kg): Histopathology of tested drug display decreased interstitial space and intercalated disc (yellow arrow) (D) PF II (250 mg/kg): Display only interstitial space (yellow arrow) (E) PF III (500 mg/kg): Display some intercalated disc (Yellow arrow) (F) Glibenclamide (10 mg/kg): Similar display live the normal control group histopathology. The samples were obtained from the same liver anatomical regions. For each group, 6 rats were examined and 50 pictures were taken. Original magnification, 40×.