Paederia Foetida Linn. leaves extract effect on pancreas histopathology in normal and STZ induced diabetic rats. (A) Normal control: Normal control group rat histopathology display the normal size of islet of langerhans (Green arrow) (B) Diabetic control: Diabetic control histopathology display the focal necrosis (yellow arrow) and bigger in the size of islets of langerhans (Black arrow). (C) PF I (100 mg/kg): PF tested drug display bigger size of islet (Black arrow) and focal necrosis (Yellow arrow). (D) PF II (250 mg/kg): PF tested drug display only focal necrosis (Yellow arrow) (E) PF III (500 mg/kg): PF tested drug display normal size of islet (Green arrow) (F) Glibenclamide (10 mg/kg): Glibenclamide treated rat pancreas showing normal islet (Green arrow). For each group 6 rats were examined and 50 pictures were taken. Original magnification, 10×.