Figure 1From: Piper betle induces phase I & II genes through Nrf2/ARE signaling pathway in mouse embryonic fibroblasts derived from wild type and Nrf2 knockout cells N0 cells display increased toxicity to PB aqueous extract. WT and N0 cells were treated with increasing doses of PB for 24 h and cell viability was assessed by the MTS assay. Mean cell viability are expressed as percentage of control. Data represent ± S.E.M from three independent experiments. a P < 0.05, compared to control; b P < 0.05, compared to WT cells at the same concentration.Back to article page