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Table 5 Effect of Ir.Cr on pyrogen-induced pyrexia in rabbit

From: In-vitro and in-vivo validation of ethnopharmacological uses of methanol extract of Isodon rugosus Wall. ex Benth. (Lamiaceae)

Groups

Treatment

Rectal temperatures

0 hr

2 hs

3 hs

4 hs

5 hs

Control

Pyrogen + Saline

38.44 ± 0.1

40.16 ± 0.2

40.12 ± 0.1

40.10 ± 0.1

40.10 ± 0.1

Ir.Cr

Pyrogen + Ir.Cr 80 mg/kg

37.9 ± 0.2

39.05 ± 0.05

38.85 ± 0.07

38.37 ± 0.02

38.37 ± 0.03

Aspirin

Pyrogen + Aspirin 10 mg/kg

38.93 ± 0.1

38.71 ± 0.2

38.06 ± 0.1

38.32 ± 0.2

39.20 ± 0.1