DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4

Table 2 Significantly enriched GO biological processes among top 0.1% candidate target-genes of DQP compositive compounds

GO term ID	Description	P-value^a
GO:0009058	Biosynthetic process	9.37E-09
GO:0006520	Cellular amino acid metabolic process	3.27E-08
GO:0034641	Cellular nitrogen compound metabolic process	3.56E-07
GO:0071941	Nitrogen cycle metabolic process	1.53E-05
GO:0006399	tRNA metabolic process	7.32E-05
GO:0044281	Small molecule metabolic process	1.16E-04
GO:0003013	Circulatory system process	1.43E-03
GO:0007267	Cell-cell signaling	3.33E-03
GO:0006950	Response to stress	3.63E-03
GO:0006412	Translation	9.13E-03
GO:0042592	Homeostatic process	1.19E-02
GO:0007568	Aging	1.60E-02
GO:0050877	Neurological system process	1.63E-02
GO:0008283	Cell proliferation	2.55E-02
GO:0008219	Cell death	4.09E-02

^aThe top 0.1% candidate target-genes are significantly enriched with genes annotated with a GO term when its corresponding upper-tailed P-value of hypergeometric cumulative distribution is smaller than 0.05. These GO terms are ranked according to the order of the increasing P-values.

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