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Figure 1 | BMC Complementary and Alternative Medicine

Figure 1

From: Subacute administration of crude khat (Catha edulis F.) extract induces mild to moderate nephrotoxicity in rats

Figure 1

Photomicrographs of hematoxilin and eiosin stained renal tissues for khat and/or gentamicin treated rats: The kidneys of the control rats (treated with Tween80) showed normal renal parenchyma with normal histo-architecture (A). On the other hand K400 rats showed mild to moderate interstitial inflammation (arrows), hypertrophied glomerular capillaries and injured dilated Bowman’s capsule (*) (B). GEN rats showed marked infiltrative inflammatory cells and vascular congestion (arrows) and vacuolar degeneration of the tubules (*) (C). Furthermore, GK400 rats revealed more extensive and marked infiltrative inflammation, complete destruction of glomerular capillaries (arrows), degeneration of the tubules and Foamy appearance in the tubular epithelial cells (*) (D). Magnification × 40. K400, khat 400 mg/kg, GEN, gentamicin 100 mg/kg, GK400, khat 400 mg/kg + gentamicin 100 mg/kg.

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