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Table 2 Predictive values of PTP1B inhibitory activity for the top five Kampo formulations used to construct the PLS model

From: Evaluation of 147 Kampo prescriptions as novel protein tyrosine phosphatase 1B (PTP1B) inhibitory agents

Kampo formula

Experimental value

Predictive value

Differencea)

Daiokanzoto

4.1

4.4

−0.3

Masiningan

4.3

3.9

0.4

Tokakujokito

4.9

5.1

−0.2

Keimakakuhanto

6.3

6.3

0.0

Choijokito

6.6

6.4

0.2

  1. Experimental value, Predictive value and Difference of each Kampo formula in the latent variable obtained by the cross- validation method are shown. The coefficient of determination in that case was 0.947. All values are expressed in μUnit/mL. a)Difference = predicted - experimental.