Figure 7
Representative section of colon architecture histology under the light microscope after haematoxylin and eosin staining. (A) Control rats with normal colon architecture. (B) azoxymethane-treated rats showed colonic mucosa with preserved architecture and lined by unremarkable epithelium in nearly two thirds of the examined area. There is an increase in mitotic activity in the crypts (arrows) compared to the control rats which may suggest regeneration in response to AOM-induced-injury. (C), (D) & (E) azoxymethane-treated rats in the presence of extracts (PapPE, PomPE and SE respectively) showed dramatic improvement in the histologic appearance similar to the control rats, There was surface autolysis in these samples but deeper crypts appear unremarkable. (F) A representative section for PapPE, PomPE or SE treated groups; showed histological appearance similar to the control rats.