Table 1 Cell lines, chemotherapeutic drug concentrations and incubation times used for the proliferation and apoptosis/necrosis assays
Cell line | Chemotherapeutic drug | Concentrations of chemotherapeutic drug (μg/ml) for | Incubation time (h) | |
|---|---|---|---|---|
Proliferation assay | Apoptosis assay | |||
HCC1937 | Doxorubicin hydroxide | 0.0; 0.1; 0.5; 1.0; 5.0 | 0.0; 0.25; 1.0; 5.0 | 48 |
HCC1143 | Doxorubicin hydroxide | 0.0; 0.1; 0.5; 1.0; 5.0 | 0.0; 0.5; 5.0 | 48 |
PA-TU-8902 | Gemcitabine hydroxide | 0.0; 0.01; 0.1; 1.0; 10.0 | 0.0; 25.0; 50.0; 100.0; 200.0 | 72 |
DU-145 | Docetaxel | 0.0; 0.0008; 0.008; 0.08; 0.8 | 0.0; 0.0008; 0.008; 0.08; 0.8 | 72 |
DU-145 | Mitoxantrone hydroxide | 0.0; 0.002; 0,02; 0,2; 2.0 | 0.0; 0.002; 0,02; 0,2; 2.0 | 72 |
NCI-H460 | Cisplatin | 0.0; 0.3; 1.0; 3.0; 9.0 | 0.0; 0.3; 1.0; 3.0; 9.0 | 48 |
NCI-H460 | Docetaxel | 0.0; 0.001; 0.01; 0.1; 1.0 | 0.0; 0.001; 0.01; 0.1; 1.0 | 48 |