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Table 4 Herbal medicines with pre-clinical evidence not included in this review

From: Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings

Herbal medicine Pre-clinical evidence for (potential) effects in reproductive endocrinology in PCOS and associated oligo/amenorrhoea and hyperandrogenism Reason for exclusion
Curcuma longa (turmeric) Anti-androgen effects [102]. No clinical evidence examining effectiveness in women was found.
Matricaria chamomilla (Chamomile) Reduced luteinising hormone and improved ovarian morphology in animals with PCOS [103]. No clinical data found.
Mentha piperita (peppermint) Anti-androgen effects in animals [104]. No clinical data for women.
Silybum marianum (St Marys thistle) Anti-proliferative antioxidant and biochemical effects in the liver [105]. No clinical evidence including women was found.
  1. Studies investigating chemical compounds derived from the herbal medicines, included in this review but investigating different outcomes were found for Vitex agnus-castus [70] and Cimicifuga racemosa [106].