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Table 3 Checkerboard assay of gentamicin and PACs against P. aeruginosa, showing the decrease (potentiation) of the gentamicin MIC by the addition of PAC

From: Cranberry proanthocyanidins have anti-biofilm properties against Pseudomonas aeruginosa

 

[Gentamicin] (μg/mL)

[PAC] (μg/mL)

 

1.7

1.6

1.5

1.4

1.3

1.2

1.1

0

100

0.081

0.084

0.079

0.088

0.178

0.698

0.841

1.74

10

0.066

0.066

0.069

0.067

0.093

0.439

0.693

1.746

1

0.057

0.055

0.054

0.059

0.07

0.461

1.137

1.743

 

0.1

0.108

0.056

0.053

0.06

0.056

0.903

1.687

1.774

 

0.01

0.056

0.054

0.063

0.053

0.062

1.002

1.197

1.794

 

0

0.054

0.061

0.055

0.241

0.647

1.267

1.727

1.806

  1. Bold value indicates point of synergy.