Skip to main content

Table 3 Representative of in vitro antiplasmodial activity of standard drugs against P. falciparum K1 strain

From: Effect of selected local medicinal plants on the asexual blood stage of chloroquine resistant Plasmodium falciparum

Drugs EC50values
  nM μg/ml
Chloroquine 149.43 0.077
Quinine 152.19 0.049
Mefloquine 23.49 0.010
Artemisinin 1.80 0.00051
  1. Data are presented as mean of three independent experiments performed in duplicate assays.
  2. The in vitro P. falciparum HRP2 assay for standard antimalarial drugs were conducted in parallel with the test plant extracts. Each of the assay were validated based on the EC50 threshold for each standard antimalarial drugs against the P. falciparum K1 strain in the lab. If the EC50 value of the standard antimalarial drugs are out of range, the test considered invalid.