Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats

Table 1 Metabolic and physical parameters

	NOR	DM	PCE-100	PCE-350
Blood glucose (mg/dl)	162.1 ± 11.0	587.3 ± 43.5*	530.3 ± 58.1	474.2 ± 88.4
Body weight (g)	475.9 ± 10.7	208.5 ± 12.1*	205.5 ± 23.1	206.0 ± 16.4

NOR, normal rat; DM, STZ-induced diabetic rat; PCE-100, DM treated with PCE (100 mg/kg); PCE-350, DM treated with PCE (350 mg/kg). All data are expressed as the mean ± SEM (n=8). *P <0.01 vs. NOR group.

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