Renal histopathology and albuminuria. (A) Periodic acid-Schiff staining of glomeruli. 400× magnification. (B) Albuminuria in the experimental group. NOR, normal rat; DM, STZ-induced diabetic rat; PCE-100, DM treated with PCE (100 mg/kg); PCE-350, DM treated with PCE (350 mg/kg). All data are expressed as the mean ± SEM (n=8). *P <0.01 vs. NOR group, # P <0.01 vs. DM group, and +P <0.01 vs. PCE-100 group.