TY - JOUR AU - Sohn, Eunjin AU - Kim, Junghyun AU - Kim, Chan-Sik AU - Jo, Kyuhyung AU - Lee, Yun Mi AU - Kim, Jin Sook PY - 2014 DA - 2014/12/11 TI - Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats JO - BMC Complementary and Alternative Medicine SP - 477 VL - 14 IS - 1 AB - Platelet-derived growth factor–BB (PDGF-BB) is highly expressed in the renal tissues of patients with diabetic nephropathy, and it plays an important role in the initiation and progression of diabetic nephropathy. The aim of this study was to evaluate the protective effects of root of Polygonum cuspidatum extract (PCE) on early renal glomerular proliferation in streptozotocin (STZ)-induced diabetic rats. SN - 1472-6882 UR - https://doi.org/10.1186/1472-6882-14-477 DO - 10.1186/1472-6882-14-477 ID - Sohn2014 ER -