|
Serum hormones
|
Week 0
|
Week 4
|
Difference from week 0 to week 4
|
P Valuea
|
|---|
|
Total testosterone
|
|
Cmax(pmol/L)
|
17.38 ± 5.57
|
17.14 ± 4.57
|
-0.24 ± 3.22
|
0.906
|
|
Tmax(h)
|
0.85 ± 2.53
|
0.84 ± 2.53
|
0.00 ± 0.00
|
0.331
|
|
AUC(0–8 hour) (pmol.h/L)
|
101.64 ± 36.38
|
99.77 ± 29.96
|
-1.87 ± 21.42
|
0.998
|
|
Free testosterone
|
|
Cmax(pmol/L)
|
44.14 ± 13.33
|
44.38 ± 14.04
|
0.24 ± 5.30
|
0.924
|
|
Tmax(h)
|
0.85 ± 2.53
|
0.63 ± 2.01
|
-0.21 ± 2.11
|
0.667
|
|
AUC(0–8 hour) (pmol.h/L)
|
245.71 ± 71.67
|
254.31 ± 64.02
|
8.60 ± 32.14
|
0.228
|
|
Estradiol-17β
|
|
Cmax(pmol/L)
|
97.74 ± 25.87
|
84.32 ± 21.05
|
-13.42 ± 17.08
|
0.004
|
|
Tmax(h)
|
1.69 ± 2.53
|
1.90 ± 3.03
|
0.21 ± 3.89
|
0.817
|
|
AUC(0–8 hour) (pmol.h/L)
|
687.08 ± 173.03
|
617.43 ± 120.00
|
-69.65 ± 88.00
|
0.002
|
- Cmax, Tmax and AUC0-8h of serum hormones following administration of 1000 mg acetaminophen to participants at week 0 and after 4 weeks of SBR supplementation.
- Values are presented as Mean ± SDa Between group comparisons were made using t-test. Statistical comparisons for Cmax and AUC(0–8 hours) were conducted using log-transformed data.
- Cmax = maximum concentration; Tmax = time of maximum concentration; AUC = area under the serum concentration time curve.
