Figure 1

Effects of PCPA on BVA-induced increases in 5-HT and TWL in oxaliplatin-injected rats. (a) Levels of 5-HT in the spinal cord measured with ELISA. Vehicle + N/S, Vehicle + BV, and PCPA + BV (n = 5/group). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, by one-way ANOVA followed by Dunnet’s test. (b) PCPA, but not vehicle pretreatment (n = 8/group), blocked the significant increase in TWL by BVA at GV3 acupoint. Data are presented as mean ± SEM. ***p < 0.001, ns = no significant, by paired t-test.