Antiplasmodial activity of solvent fractions of methanolic root extract of Dodonaea angustifolia in Plasmodium berghei infected mice

Table 1 Effect of n-butanol fraction of methanolic root extract of D. angustifolia on percent parasitaemia and mean survival time of the mice

Treatment	Dose mg/kg	%Parasitaemia	%Chemosuppression	Mean survival time
n-butanol fraction	200	34.02 ± 2.29	38.02^c	10.33 ± 1.76^a
	400	24.24 ± 3.42	55.85^c	10.79 ± 1.37^a
	600	17.83 ± 4.11	67.51^c	11.37 ± 1.61^b
Chloroquine	10	0	100	14.19 ± 0.84
Distilled water	1 ml	54.90 ± 4.39	0	7.79 ± 0.73

a = P < 0.05, b = P < 0.01, c = P < 0.001, parasitaemia and survival time expressed as mean ± SD, n = 5, the results are expressed as the percent suppression of parasitaemia with reference to non-treated mice. distilled water = control.

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