Figure 3From: Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress Effects of NNAV on the histopathological changes in the lung tissue (HE staining and Masson’s trichrome staining, ×400). Animals were treated as described in the legend to Figure 1. Lung tissue was fixed in 10% formalin, sectioned and stained with HE and trichrome. Inflammatory cell infiltration (▲) and the blue color collagen deposition (↑) in the lung tissue were found. HE staining: (A) Six h after LPS. (a) Control. (b) LPS. (c) LPS + NNAV 30 μg/kg. (d) LPS + NNAV 90 μg/kg. (e) LPS + NNAV 270 μg/kg. (B) Eight weeks after LPS. (a) Control. (b) LPS-treated lung. (c) LPS + NNAV 30 μg/kg. (d) LPS + NNAV 90 μg/kg. (e) LPS + NNAV 270 μg/kg. (C) Eight week after BLM. (a) Control. (b) BLM. (c) BLM + NNAV 30 μg/kg. (d) BLM + NNAV 90 μg/kg. (e) BLM + NNAV 270 μg/kg. (D) Masson’s trichrome staining: D(a) Control. D(b) BLM. D(c) BLM + NNAV 30 μg/kg.D(d) BLM + NNAV 90 μg/kg. D(e) BLM + NNAV 270 μg/kg.Back to article page