Experimental assessment of antidiarrheal and antisecretory activity of 80% methanolic leaf extract of Zehneria scabra in mice

Table 5 The effect of Z. scabra extract on intestinal transit in mice using charcoal meal as a marker

Group	Total length of intestine (cm)	Distance travelled by charcoal (cm)	% Intestinal transit	% Inhibition relative to control
2%TW-80	59.2 ± 1.48)	53.7 ± 6.41^a	90.6 ± 9.2^a	-
Atropine	57.1 ± 2.86	0 ± 0.0	0.0 ± 0.0	100
ZS100	56.6 ± 5.86	49.1 ± 6.0^a	86.9 ± 8.4^a	4.1
ZS200	59.9 ± 4.793	51.6 ± 2.9^a	86.1 ± 5.9^a	4.9
ZS400	55.8 ± 6.80	43.8 ± 9.8^a	78.0 ± 9.4^a	13.9

Values are mean length of intestine ± S.E (n=5). ^a p<0.001 values compared with the positive control.

ISSN: 2662-7671