Experimental assessment of antidiarrheal and antisecretory activity of 80% methanolic leaf extract of Zehneria scabra in mice

Table 2 The effect of Z. scabra extract on stool score scale in castor oil- induced diarrhea in mice

Group	Onset of diarrhea	Mean stool score	Number of wet feces	% Inhibition of diarrhea
2%TW-80	66.4±3.06	2.68 ± 0.05^a	19.4 ± 2.44^a	-
Lop3	180.5±15.45	1.49 ± 0.093***	3 ± 0.89***	84.5
ZS100	100.33±8.41	2.34 ± 0.098*^a	9.3 ± 1.20***^b	52.1
ZS200	118.33±7.34	1.94 ± 0.102***^b	7 ± 0.85***	63.9
ZS400	140.00±16.48	2.26 ± 0.119**^a	6.5 ± 0.81***	66.5

Values are mean ± S.E (n=5) ***p<0.001 values compared with the negative control; **p<0.01 values compared with the negative control, *p<0.05 values compared with the negative control. ^ap<0.001 values compared with the positive control; ^bp<0.01 values compared with the positive control.

ISSN: 2662-7671