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Table 2 Protective effect of curcumin on paracetamol induced changes in serum levels of renal and hepatic parameters in Wistar rats

From: Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats

  Control Curcumin Paracetamol Curcumin + Paracetamol
Urea (mg/dl) 35.6 ± 3.8 35.3 ± 2.3 42.0 ± 1.5* 31.0 ± 1.0#
Albumin (g/dl) 3.2 ± 0.1 3.1 ± 0.1 4.8 ± 0.4* 3.5 ± 0.1#
GOT (U/L) 83 ± 2 72.7 ± 9.6 156 ± 9.4* 90.3 ± 3.7#
GPT(U/L) 58.3 ± 6 64.7 ± 6.01 136 ± 27.9* 98 ± 4.9#
  1. Values are means ± standard error (SEM) for 3 independent experiments per each treatment. Values are statistically significant at *p < 0.05 Vs. control and #p < 0.05 Vs. paracetamol group.