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Table 2 Protective effect of curcumin on paracetamol induced changes in serum levels of renal and hepatic parameters in Wistar rats

From: Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats

 

Control

Curcumin

Paracetamol

Curcumin + Paracetamol

Urea (mg/dl)

35.6 ± 3.8

35.3 ± 2.3

42.0 ± 1.5*

31.0 ± 1.0#

Albumin (g/dl)

3.2 ± 0.1

3.1 ± 0.1

4.8 ± 0.4*

3.5 ± 0.1#

GOT (U/L)

83 ± 2

72.7 ± 9.6

156 ± 9.4*

90.3 ± 3.7#

GPT(U/L)

58.3 ± 6

64.7 ± 6.01

136 ± 27.9*

98 ± 4.9#

  1. Values are means ± standard error (SEM) for 3 independent experiments per each treatment. Values are statistically significant at *p < 0.05 Vs. control and #p < 0.05 Vs. paracetamol group.