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Figure 1 | BMC Complementary and Alternative Medicine

Figure 1

From: Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats

Figure 1

Photographs of liver histopathology from CTR, CUR, PRM, and CUR + PRM administered rats stained with H & E. A, liver of CTR group showing normal hepatic architecture with presence of a central vein (CV) surrounded by normal radiating hepatic cords (arrow). B, liver of CUR group showing normal hepatic lobules, consisting of a central vein (cv) surrounded by radiating hepatocyte plates with normal portal tracts (PT) surround the classical lobules. C, liver of PRM intoxicated group showing extensive coagulative necrosis of hepatocytes (N) together with dense leukocytic infiltration (neutrophils and lymphocytes; LI). D, liver of CUR + PRM administered group showing improvement of hepatic toxicity with presence of small degenerated areas (*). Scale bar for all photographs is 100 μm. Inserts are high magnification fields in C and D with scale bars of 50 μm.

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