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Table 1 Minimun inhibitory concentration (MIC in mg/ml) of extracts and fractions from S. spinosa against fungi and bacteria

From: Some Strychnos spinosa (Loganiaceae) leaf extracts and fractions have good antimicrobial activities and low cytotoxicities

  Fungia Bacteriab
Samples C. a C.A A.f C.nc S.a B.c E.f E.c
  16 h 24 h 16 h 24 h 16 h 24 h 24 h 36 h 1 h 2 h 1 h 2 h 1 h 2 h 1 h 2 h
Extracts d                 
AcetE >1.25 >1.25 >1.25 >1.25 1.25 >1.25 0.63 0.63 0.16 0.16 0.32 0.32 0.16 0.16 0.32 1.25
MetE >1.25 >1.25 >1.25 >1.25 1.25 1.25 0.63 0.63 >1.25 >1.25 >1.25 >1.25 >1.25 >1.25 0.63 0.63
DcmMetE >1.25 >1.25 >1.25 >1.25 1.25 1.25 0.16 0.16 0.63 0.63 >1.25 >1.25 0.63 0.63 0.63 0.63
AlkE >1.25 >1.25 >1.25 >1.25 >1.25 >1.25 0.32 0.32 0.16 0.16 1.25 >1.25 0.32 0.32 0.16 1.25
Fractions e                 
HexF 1.25 1.25 0.63 0.63 >1.25 >1.25 0.32 1.25 0.08 0.08 0.63 1.25 0.32 0.32 0.08 1.25
ChlF 0.16 0.16 0.63 0.63 0.08 0.08 0.32 1.25 0.08 0.08 0.63 0.63 0.16 0.16 0.16 0.32
EtAcF 0.63 0.63 0.16 0.16 0.08 0.08 0.32 1.25 0.16 0.16 0.63 1.25 0.16 0.32 0.16 1.25
nBuF >1.25 >1.25 >1.25 >1.25 1.25 1.25 0.04 1.25 0.08 0.16 0.63 0.63 1.25 1.25 0.63 0.63
WatF >1.25 >1.25 >1.25 >1.25 1.25 1.25 0.63 >1.25 >1.25 >1.25 >1.25 >1.25 >1.25 >1.25 1.25 >1.25
Controls f                 
Amp B 16 16 8 8 16 16 > 250 > 250 - - - - - - - -
Gen - - - - - - - - 0.78 0.78 0.39 0.39 1.56 1.56 0.39 0.39
  1. a)C.a: Candida albicans(Isolate); C.A: Candida albicans (ATCC strain); C.n: Cryptococcus neoformans; A.f: Aspergillus fumigatus, b)E.c: Escherichia coli; E.f: Enterococcus faecalis; S.a: Staphylococcus aureus; B.c: Bacillus cereus, c)with this microorganism litle reaction was observed after 16 h and MIC were recorded after 24 h and 36 h, d)AcetE: Acetone Extract, MetE: Methanol extract, DcmMetE: Dichloromethane/methanol extract, AlkE: Alkaloids extract, e)HexF: n-hexane fraction, ChlF: Chloroform fraction, EtAcF: Ethyl acetate fraction, nBuF: n-Butanol fraction, WatF: Water fraction, f)Amp B: Amphotericin B (in μg/ml), Gen: Gentamicin (in μg/ml). In bold are values with significant activity.
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