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Table 1 Effects of GGDGT on body weight, water intake, food intake, blood glucose, and blood pressure levels in ApoE-/- mice

From: Gal-geun-dang-gwi-tang improves diabetic vascular complication in apolipoprotein E KO mice fed a western diet

  Weeks
   0 4 8 11
Body weight (g) Control 22.33 ± 0.67 24.08 ± 0.79 25.73 ± 0.79 27.42 ± 0.87
ApoE -/- 22.57 ± 0.65 28.23 ± 0.70** 33.60 ± 1.01** 37.55 ± 0.90**
Rosiglitazone 22.07 ± 0.59 27.25 ± 0.97# 31.77 ± 1.22## 34.47 ± 1.35##
GGDGT 21.45 ± 0.35 25.42 ± 0.56# 29.95 ± 0.95## 32.43 ± 1.16##
Water intake (g/day) Control 37.63 ± 2.19 44.68 ± 2.15 39.38 ± 3.00 50.59 ± 0.67
ApoE -/- 38.98 ± 2.92 31.31 ± 2.68 23.21 ± 1.97 30.53 ± 3.07
Rosiglitazone 38.74 ± 3.01 30.08 ± 0.72 25.05 ± 0.71 22.68 ± 1.28
GGDGT 29.62 ± 2.11 23.18 ± 1.82 21.30 ± 1.53 24.45 ± 2.00
Food intake (g/day) Control 19.87 ± 0.45 24.33 ± 0.93 20.85 ± 0.52 20.65 ± 0.55
ApoE -/- 18.06 ± 0.31 18.37 ± 0.26 17.58 ± 0.49 15.98 ± 0.42
Rosiglitazone 16.58 ± 0.35 15.00 ± 0.22 14.02 ± 0.62 12.77 ± 0.79
GGDGT 17.60 ± 0.52 16.24 ± 0.33 16.17 ± 0.20 14.11 ± 0.43
Glucose (mg/dl) Control 119.60 ± 1.63 114.00 ± 5.30 102.00 ± 2.48 113.67 ± 3.48
ApoE -/- 123.80 ± 9.28 104.00 ± 6.66 114.60 ± 6.87 138.25 ± 3.42**
Rosiglitazone 127.33 ± 7.54 95.25 ± 14.44 097.75 ± 2.75 113.75 ± 3.25##
GGDGT 129.33 ± 4.37 98.67 ± 1.48 107.50 ± 3.27 118.20 ± 3.64##
Systolic blood pressure (mmHg) Control 102.06 ± 1.47 103.16 ± 1.2 104.16 ± 1.33 109.00 ± 0.91
ApoE -/- 102.83 ± 1.98 110.42 ± 1.56 117.32 ± 1.75 128.83 ± 1.62**
Rosiglitazone 101.53 ± 1.68 104.20 ± 0.93 104.95 ± 1.17 110.03 ± 0.76##
GGDGT 111.25 ± 1.32 106.80 ± 1.02 106.90 ± 0.95 112.15 ± 0.82##
  1. Body weight expressed the mean of absolute weight of mice. ApoE-/-, apolipoprotein E knockout mouse; Rosiglitazone, WD + 10 mg/day/kg rosiglitazone; GGDGT, WD + 200 mg/day/kg GGDGT. Values are expressed as mean ± S.E. values (n = 12). **p < 0.01, vs. RD-fed control mice; #p < 0.05, ##p < 0.01 vs. WD-fed ApoE-/- mice.