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Table 5 Effect of SME on antioxidant profile

From: CCl4 induced genotoxicity and DNA oxidative damages in rats: hepatoprotective effect of Sonchus arvensis

Treatment CAT (U/min ) SOD (U/mg protein) GSH-Px nM/min/mg protein GSH (μM /min/mg protein) GSR nM/min/mg protein) TBARS(nM /min/mg protein)
Control 6.0 ± 0.5++ 18.7 ± 2.8++ 64.7 ± 3.9++ 2.12 ± 0. 2++ 121.7 ± 6.4++ 29.3 ± 1.2++
3 ml/kg CCl4 2.9 ± 0.6** 9.9 ± 0.7** 34.2 ± 6.3** 1.03 ± 0.3** 67.3 ± 3.5** 53.17 ± 1.2**
100 mg/kg SME + CCl4 5.0 ± 0.7++ 16.5 ± 0.7++ 52.4 ± 7.8++ 1.90 ± 0.1++ 111.2 ± 12.4++ 38.7 ± 2.6++
200 mg/kg SME + CCl4 5.8 ± 0.9++ 17.5 ± 0.8++ 62.7 ± 5.6 2.03 ± .07 122.33 ± 5.28++ 31.17 ± 1.4++
100 mg/kg sylimarin + CCl4 5.7 ± 0.5++ 19.4 ± 0.3++ 60.2 ± 5.3++ 2.17 ± 0.04++ 115.3 ± 9.14+ 30.0 ± 2.7++
200 mg/kg SME alone 5.9 ± 0.6++ 20.9 ± 0.5++ 66.8 ± 3.3++ 2.09 ± 0.2++ 120.2 ± 6.3++ 31.2 ± 2.7++
  1. Mean ± SE (n = 6 number).
  2. **indicate significance from the control group at P < 0.01 probability level.
  3. ++indicate significance from the CCl4 group at P < 0.01 probability level.
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