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Table 3 Effect of SME on liver markers enzymes

From: CCl4 induced genotoxicity and DNA oxidative damages in rats: hepatoprotective effect of Sonchus arvensis

Treatment

AgNORS (NORs/cell)

%DNA fragmentation

Control

2.0 ± 0.33++

5.33 ± 2.46++

3 ml/kg CCl4

6.4 ± .29**

22.50 ± 3.68**

100 mg/kg SME + CCl4

3.1 ± 0.35*++

5.00 ± 1.83++

200 mg/kg SME + CCl4

3.5 ± 0.18**++

6.67 ± 2.08++

100 mg/kg sylimarin + CCl4

2.14 ± 0.23++

5.67 ± 3.12++

200 mg/kg SME alone

1.9 ± 0.17**++

4.67 ± 2.23++

  1. Mean ± SE (n = 6 number).
  2. **indicate significance from the control group at P < 0.05 and P < 0.01 probability level.
  3. ++indicate significance from the CCl4 group at P < 0.05 and P < 0.01 probability level.