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Table 2 Effect of SME on liver markers enzymes

From: CCl4 induced genotoxicity and DNA oxidative damages in rats: hepatoprotective effect of Sonchus arvensis

Treatment ALT(U/L) AST(U/L) ALP(U/L) γ-GT(nM/min /mg protein)
Control 45.8 ± 3.2++ 53.8 ± 3.4++ 148 ± 5.9++ 105.5 ± 2.2++
3 ml/kg CCl4 102 ± 4.2** 94.0 ± 4.7** 340.3 ± 6.9** 154.3 ± 3.2**
100 mg/kg SME + CCl4 68 ± 3.8++ 62.3 ± 4.9++ 207.5 ± 4.9++ 121.3 ± 3.4++
200 mg/kg SME + CCl4 91 ± 2.2++ 56 ± 4.1++ 167.7 ± 5.7++ 108 ± 2.7++
100 mg/kg sylimarin + CCl4 89 ± 1.5++ 57.5 ± 2.0++ 157.8 ± 3.9++ 110 ± 3.5++
200 mg/kg SME alone 97 ± 2.4++ 49.5 ± 3.6++ 145.3 ± 5.1++ 103 ± 2.7++
  1. Mean ± SE (n = 6 number).
  2. **indicate significance from the control group at P < 0.05 and P < 0.01 probability level.
  3. ++indicate significance from the CCl4 group at P < 0.05 and P < 0.01 probability level.
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