Table 2 IC ₅₀ values ( μ g/mL) of ROS inhibitory and chemotaxis activities of Phyllanthus amarus and P. urinaria and their major compounds on phagocytes (mean ± SEM, n =3)

PA (Mal)

1.22 ± 0.10

1.44 ± 0.80

0.95 ± 0.24

0.58 ± 1.80

0.10 ± 0.17

1.24 ± 0.98

0.42 ± 0.75

0.56 ± 0.30

PA (Ind)

1.84 ± 0.01

2.35 ± 0.23

8.14 ± 1.71

0.12 ± 0.05

2.19 ± 2.55

6.02 ± 1.33

1.34 ± 0.59

1.27 ± 0.80

PU (Mal)

1.46 ± 0.10

2.84 ± 0.30

1.52 ± 0.53

1.00 ± 1.21

1.23 ± 0.88

1.98 ± 1.09

0.45 ± 0.23

0.26 ± 0.12

PU (Ind)

2.21 ± 0.90

2.92 ± 0.14

9.74 ± 1.09

1.64 ± 0.58

0.36 ± 0.29

4.80 ± 1.80

1.34 ± 1.18

1.06 ± 0.31

GA

1.40 ± 0.02 (8.22 ± 0.15)

2.00 ± 0.03 (11.75 ± 0.23)

1.70 ± 0.03 (9.99 ± 0.12)

0.43 ± 1.02 (2.53 ± 0.10)

1.29 ± 0.87 (7.58 ± 0.50)

0.87 ± 0.12 (5.11 ± 0.15)

0.48 ± 0.01 (2.82 ± 0.15)

1.28 ± 0.01 (7.52 ± 0.12)

EA

1.33 ± 0.07 (4.40 ± 0.12)

1.81 ± 0.12 (5.96 ± 0.12)

1.36 ± 0.08 (4.50 ± 0.16)

0.56 ± 0.02 (1.85 ± 0.35)

0.45 ± 0.09 (1.49 ± 0.07)

0.83 ± 0.03 (2.75 ± 0.07)

0.31 ± 0.07 (1.02 ± 0.06 )

0.75 ± 0.12 (2.48 ± 0.06 )

Ger

1.04 ± 0.12 (1.09 ± 0.23 )

1.61 ± 0.14 (1.69 ± 0.05)

0.34 ± 0.30 (0.36 ± 0.12 )

0.18 ± 0.07 (0.18 ± 0.02)

0.37 ± 0.41 (0.38 ± 0.07)

0.19 ± 0.12 (0.21 ± 0.01)

0.12 ± 0.04 (0.13 ± 0.01)

0.36 ± 0.61 (0.38 ± 0.12 )

Cor

1.49 ± 0.024 (2.34 ± 0.07)

1.99 ± 0.09 (3.13 ± 0.44)

0.37 ± 0.37 (0.58 ± 0.03)

0.36 ± 0.07 (0.56 ± 0.023)

0.44 ± 0.08 (0.69 ± 0.12)

0.22 ± 0.88 (0.35 ± 0.09)

0.15 ± 0.04 (0.24 ± 0.02)

0.44 ± 0.03 (0.69 ± 0.05)

Phyll

3.20 ± 0.15 (7.60 ± 0.10)

8.51 ± 0.52 (20.2 ± 0.40)

3.70 ± 2.80 (8.80 ± 1.00)

3.2 ± 2.81 (7.6 ± 0.40)

2.38 ± 1.44 (5.68 ± 0.31)

1.40 ± 1.72 (3.34 ± 0.05)

0.08 ± 0.66 (0.20 ± 0.01)

1.54 ± 0.87 (3.68 ± 0.43)

Hypophyll

4.40 ± 0.2 (10.2 ± 0.40)

9.60 ± 0.26 (22.3 ± 0.53)

3.6 ± 1.40 (8.4 ± 1.30)

6.1 ± 2.32 (14.2 ± 1.70)

1.41 ± 0.06 (3.27 ± 0.15)

1.87 ± 0.01 (4.34 ± 0.02)

0.95 ± 0.11 (2.20 ± 0.31)

1.73 ± 0.31 (4.02 ± 0.71)

Ibuprofen

1.40 ± 0.10 (6.60 ± 0.10)

1.98 ± 0.05 (9.57 ± 0.23)

Aspirin

2.16 ± 0.80 (11.88 ± 4.14)

0.85 ± 0.20 (4.68 ± 2.71)

0.43 ± 0.07 (2.40 ± 0.16)

0.17 ± 0.01 (0.94 ± 0.05)

0.14 ± 0.09 (0.77 ± 0.16)

0.58 ± 0.28 (3.22 ± 0.38)