TY - JOUR AU - Liu, Bao-Xin-Zi AU - Zhou, Jin-Yong AU - Li, Yu AU - Zou, Xi AU - Wu, Jian AU - Gu, Jun-Fei AU - Yuan, Jia-Rui AU - Zhao, Bing-Jie AU - Feng, Liang AU - Jia, Xiao-Bin AU - Wang, Rui-Ping PY - 2014 DA - 2014/10/24 TI - Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway JO - BMC Complementary and Alternative Medicine SP - 412 VL - 14 IS - 1 AB - Colorectal cancer has become one of the leading cause of cancer morbidity and mortality throughout world. Hederagenin, a derivative of oleanolic acid isolated from the leaves of ivy (Hedera helix L.), has been shown to have potential anti-tumor activity. The study was conducted to evaluate whether hederagenin could induce apoptosis of human colon cancer LoVo cells and explore the possible mechanism. SN - 1472-6882 UR - https://doi.org/10.1186/1472-6882-14-412 DO - 10.1186/1472-6882-14-412 ID - Liu2014 ER -