Antiangiogenic effect of selected Sudanese plants (100 μg/ml) against sprouting of microvessels in rat aortic explants. A) Photomicrographic image of rat aortic ring of negative control showing extensive growth of microvessels. B) Photomicrographic image of rat aortic ring representative of polar extract of T. apollinea displaying potent inhibition of growth of microvessels. C) Treatment with T. nilotica showed significant inhibitory effect against sprouting of microvessels from rat aortic rings. D) Photomicrographic image of rat aortic explant treated with C. hartmannianum extract demonstrated considerable effect of antiangiogenicity. E) Photomicrographic image of rat aortic explant treated with non-polar extract of T. apollinea showing significant inhibitory effect on growth of microvessels. F) Photomicrographic image of rat aortic explant treated with standard reference, suramin exhibiting strong inhibitory effect on microvessels growth. G) Graphical representation of antiangiogenic activity of the active extracts obtained from the selected Sudanese plants. The values are expressed as mean ± SEM (n =10). **p < 0.01 and *p < 0.05 compared to negative control group (0.1% DMSO).