Figure 7

Survival of C. elegans is improved over time upon supplementation of extracts and compounds. (A and B) The survival curves of S. aureus-infected C. elegans upon exposure to selected hit extracts (200 μg/mL) and compounds (200 μM). Enhanced survival of infected worms can be seen in the presence of extracts UE-01-2, UE-03-5, UE-08 (A) and compounds UC-10, UC-12 and UC-15 (B). Data at each time point are the average of three wells with each well containing approximately 10–15 animals per well. In a pair-wise comparison to no extract using log-rank tests, the difference between all of the treatments was significant (p < 0.0001).