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Table 5 Collagenase inhibition activity of CPE, AA and PBE with NNGH at 1.3 μM for positive control inhibitor

From: Phenolic composition, antioxidant, anti-wrinkles and tyrosinase inhibitory activities of cocoa pod extract

Sample

Concentration (μg/ml)

IC 50     

 

7.8    

15.6    

31.3    

62.5    

125    

250    

500    

1000    

 

NNGH, 1.3 μM

95.91 ± 0.23a

-

  AA

31.87 ± 3.40cα

44.06 ± 0.07cβ

48.70 ± 2.92cγ

33.84 ± 1.00dα

31.70 ± 2.36cα

61.75 ± 8.51bcδ

52.91 ± 4.24aγ

90.16 ± 1.27aε

261.38

  PBE

54.96 ± 6.77bδε€

50.81 ± 0.90bδ

53.32 ± 0.53bε

54.04 ± 1.48bε

16.79 ± 2.27dα

60.56 ± 4.98c€

46.00 ± 1.64bγ

39.26 ± 3.98cβ

356.01

  CPE

53.15 ± 0.95bδ

48.81 ± 2.55bγ

53.23 ± 0.41bδ

50.71 ± 0.31cγ

38.53 ± 4.22bβ

68.71 ± 2.12bε

29.97 ± 1.36cα

71.44 ± 2.28bε

111.29

  1. a b c dDifferent alphabet in column means significantly different within sample.
  2. α β γ δ ε € £different symbol means significantly different within concentration for each sample in row.