Animal Groups
|
Animal Groups
|
pH of Gastric tissue
|
Mucus Weight (g)
|
Ulcer area (mm)2
|
Inhibition (%)
|
MDA (μmol/g protein)
|
SOD (U/g protein)
|
Nitric oxide (μmol/g protein)
|
---|
A
|
Normal control
|
7.02 ± .004
|
0.89 ± 0.03
|
-
|
-
|
10 ± 1.1
|
528 ± 16.51
|
10 ± 1.3
|
B
|
Lesion control
|
2.99 ± 0.17
|
0.41 ± 0.01
|
880 ± 16.23
|
-
|
28 ± 2.98
|
333 ± 9.98
|
5.9 ± 0.47
|
C
|
Treatment control
|
6.14 ± 0.24*
|
0.79 ± 0.03*
|
195 ± 8.97*
|
77
|
13 ± 0.71*
|
481 ± 12.22*
|
9.1 ± 1.4*
|
D
|
CPRHE (200 mg/kg)
|
4.47 ± 0.09*
|
0.68 ± 0.02*
|
455 ± 12.24*
|
48
|
21 ± 0.22*
|
393 ± 7.67*
|
7.6 ± 0.8*
|
E
|
CPRHE (400 mg/kg)
|
5.82 ± 0.41*
|
0.72 ± 0.02*
|
325 ± 10.67*
|
63
|
17 ± 0.41*
|
459 ± 10.73*
|
8.4 ± 0.9*
|
- All values are expressed as mean ± SD. *indicates (P <0.05) compared to the (B) lesion control group. CPRHE: C. purpurascens rhizome hexane extract.