Animal groups
|
Serum biochemical analysis
|
---|
|
(a) Kidney biochemical parameters
|
---|
|
Sodium (mM/L)
|
Potassium (mM/L)
|
Chloride (mM/L)
|
Co2(mM/L)
|
Anion (mM/L)
|
Urea (mM/L)
|
Creatinine ( μ M/L)
|
---|
Vehicle
|
142.23 ± 0.45
|
4.85 ± 0.06
|
104.59 ± 0.45
|
23.89 ± 0.64
|
19.36 ± 0.48
|
5.28 ± 0.58
|
30.75 ± 1.87
|
CPRHE (1 g/kg)
|
143.54 ± 0.37
|
5.12 ± 0.72
|
106.24 ± 0.54
|
21.49 ± 0.73
|
19.58 ± 0.75
|
5.93 ± 0.43
|
29.81 ± 2.27
|
CPRHE (2 g/kg)
|
143.85 ± 0.82
|
4.91 ± 0.034
|
105.27 ± 0.56
|
22.85 ± 0.48
|
19.95 ± 0.39
|
5.68 ± 0.37
|
31.46 ± 2.19
|
Animal groups
|
(b) Liver biochemical parameters
|
|
Total protein (g/L)
|
Albumin (g/L)
|
Globulin (g/L)
|
TB (
μ
mol/L)
|
CB (
μ
mol/L)
|
AP (IU/L)
|
ALT (IU/L)
|
AST (IU/L)
|
GGT (IU/L)
|
Vehicle
|
60.76 ± 0.94
|
9.56 ± 0.39
|
51.07 ± 1.28
|
2.19 ± 0.13
|
0.87 ± 0.17
|
154.45 ± 5.37
|
50.49 ± 1.34
|
173.82 ± 5.38
|
3.45 ± 0.27
|
CPRHE (1 g/kg)
|
58.37 ± 0.57
|
8.35 ± 0.53
|
50.68 ± 1.32
|
2.14 ± 0.16
|
0.91 ± 0.14
|
153.23 ± 5.87
|
45.65 ± 1.74
|
175.48 ± 6.49
|
3.37 ± 0.53
|
CPRHE (2 g/kg)
|
59.67 ± 1.29
|
8.87 ± 0.19
|
50.25 ± 1.45
|
2.15 ± 0.14
|
0.84 ± 0.16
|
155.73 ± 6.82
|
46.76 ± 1.48
|
176.27 ± 6.52
|
3.57 ± 0.43
|
Animal groups
|
(c) Hematological parameters
|
|
HGB (g/dL)
|
HCT (%)
|
RBC (10
6
/μL)
|
MCV (fL)
|
MCH (pg)
|
MCHC (g/dL)
|
RDW (%)
|
WBC (10
3
/μL)
|
Platelet (10
3
/μL)
|
Vehicle
|
15.03 ± 0.13
|
46 ± 0.00
|
9.38 ± 0.13
|
59.12 ± 0.65
|
19.25 ± 0.31
|
34.22 ± 0.19
|
17.03 ± 0.44
|
6.12 ± 0.47
|
986.75 ± 23.65
|
CPRHE (1 g/kg)
|
15.47 ± 0.13
|
46 ± 0.00
|
9.64 ± 0.18
|
58.54 ± 0.63
|
18.89 ± 0.36
|
34.04 ± 0.33
|
18.23 ± 0.58
|
6.23 ± 0.34
|
995.36 ± 25.32
|
CPRHE (2 g/kg)
|
15.98 ± 0.12
|
46 ± 0.00
|
9.83 ± 0.16
|
57.78 ± 0.76
|
18.59 ± 0.29
|
33.93 ± 0.28
|
18.77 ± 0.34
|
6.31 ± 0.39
|
1011.52 ± 23.18
|
- Values expressed as mean ± SEM. ALT, alanine aminotransferase; AST, aspartate aminotransferase; AP, alkaline phosphatase; CB, conjugated bilirubin; GGT: G-glutamyl transferase; HCT, hematocrit; HGB, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; RBC, red cell count; RDW, red cell distribution width; TB: total bilirubin; WBC, white cell.
- The results did not show any significant difference between groups.