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Table 1 The 25 differentially expressed proteins between NC and NA rats

From: Non-specific physiological background effects of acupuncture revealed by proteomic analysis in normal rats

Spot No. Protein name Gene symbol Swiss-prot No. Theoretical Mr (kDa)/PI Pept./Cov%a) Fold changeb)
1 Alpha-1-antiproteinase Serpina1 P17475 46.1/5.7 6/11.68% ↓2.62
2 Gama-enolase Eno2 P07323 47.0/7.0 2/5.07% ↓3.2
3 Calreticulin Calr P18418 48.0/4.3 49/36.06% ↓5.78
4 Phosphatidylethanolamine-binding protein 1 Pebp1 P31044 20.8/5.5 9/25.13% ↓2.51
5 Actin, alpha skeletal muscle Acta1 P68136 42.0/5.2 29/22.02% ↓2.49
6 Actin, cytoplasmic 1 Actb P60711 41.7/5.3 13/10.67% ↑4.17
7 Beta-enolase Eno3 P15429 47.0/7.0 2/5.07% ↓3.29
8 Creatine kinase B-type Ckb P07335 42.7/5.4 2/4.46% ↑3.18
9 Actin, alpha skeletal muscle Acta1 P68136 42.0/5.2 8/11.94% ↑4.58
10 serum albumin precursor Alb P02770 68.7/6.0 7/6.58% ++ c)
11 Heat shock cognate 71 kDa protein Hspa8 P63018 70.9/5.4 35/30.03% ↑2.26
12 Transgelin 2 Tagln2 Q5XFX0 23.4/7.6 15/32.38% ++
13 Creatine kinase B-type Ckb P07335 42.7/5.4 2/4.46% ↑2.27
14 Fibrinogen beta chain Fgb P14480 54.2/7.9 55/45.3% -- d)
15 Heat shock cognate 71 kDa protein Hspa8 P63018 70.9/5.4 19/18.89% ↑3.16
16 Glyceraldehyde-3-phosphate dehydrogenase Gapdh P04797 35.8/8.1 20/20.12% ↑3.36
17 22 kDa protein — — 21.9/9.8 7/25.00% ↑2.21
18 Heterogeneous nuclear ribonucleoproteins A2/B1 Hnrnpa2b1 A7VJC2 37.4/9.0 46/36.83% ↑3.1
19 Tubulin alpha-1A chain Tuba1a P68370 50.1/4.9 2/5.32% ↓17.16
20 Phosphoglycerate mutase 1 Pgam1 P25113 28.8/6.7 11/16.93% --
21 Serum albumin precursor Alb P02770 68.7/6.0 39/30.59% ↑2.5
22 NG,NG-dimethylarginine dimethylaminohydrolase 2 Ddah2 Q6MG60 29.7/5.7 6/11.93% ++
23 Annexin A5 Anxa5 P14668 35.7/4.9 14/23.20% ++
24 Advanced glycosylation end product-specific receptor Ager Q63495 42.7/5.8 7/8.21% ↑2.37
25 Peroxiredoxin-6 Prdx6 O35244 24.8/5.6 13/26.34% --
  1. a)The number of matching peptides (Pept.) and percentage of the total amino acid sequence covered by the peptides (% Seq. Cov) from the mass mapping experiments.
  2. b)The change level in optical density of the protein spots in NA rats compared with NC rats.
  3. c)++ represents spots detected in gels from the NA samples but not detected in NC samples, which was considered up-regulated in the NA group.
  4. d)-- represents spot detected in gels from the NC samples but not detected in NA samples, which was considered down-regulated in the NA group.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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