Effect of DHSGT on body weight and adipocyte size in HFD-induced obese mice. (A) Body weight in obese mice fed HFD for 7 weeks. (B) Adipocyte area, and (C) representative images of hematoxylin and eosin-stained visceral fat sections (original magnification 400×). Values are expressed as means ± SEM (n = 5 animals/group). Significant differences were observed between the Control and HFD groups: ##, p < 0.01; ###, p < 0.001. Significant differences were observed between the HFD and HFD-DHSGT groups: **, p < 0.01; ***, p < 0.001. HFD, high-fat diet; DHSGT, Dohaekseunggi-tang.