Figure 3

Effects of ISSE on the recruitment of inflammatory cells to lung tissue (A) and mucus production (B). Histological examination of lung tissues was performed 48 h after the final OVA challenge. Lung tissues were stained with H&E (A) and PAS (B). NC, negative control (PBS only); OVA, OVA-sensitized/challenged mice; Mon, montelukast (30 mg/kg) + OVA-sensitized/challenged mice; ISSE-100, ISEE (100 mg/kg) + OVA-sensitized/challenged mice; ISSE-200, ISEE (200 mg/kg) + OVA-sensitized/challenged mice.