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Table 1 Cardiovascular parameters in two-kidney, one-clip Goldblatt hypertensive rats after 6 weeks of daily oral treatment with captopril (30 mg/kg per day), low-dose DAL (210 mg/kg per day) (DAL-L) and high-dose DAL (420 mgkg/per day) (DAL-H), compared with untreated controls (model) and sham-operated rats (sham)

From: Aqueous extract of dioscorea opposita thunb. normalizes the hypertension in 2K1C hypertensive rats

Parameter Sham Model Captopril DAL-L DAL-H
BW (g) 572.21 ± 84.23 586 ± 110.32 456.21 ± 44.46# 546.21 ± 74.12 552.43 ± 47.87
HW (g) 1.46 ± 0.17 2.0 ± 0.27* 1.50 ± 0.17# 1.47 ± 0.22# 1.62 ± 0.19*,#,
LHW (mg) 268.2 ± 0.03 396.2 ± 0.09* 239.3 ± 0.02*,# 300.3 ± 0.04*,# 310.6 ± 0.03*,#,
HW/BW 2.55 ± 0.45 3.56 ± 0.72* 3.05 ± 0.44*,# 2.9 ± 0.55*,# 2.41 ± 0.38*,#,
LVAWTh 0.28 ± 0.03# 0.42 ± 0.06* 0.25 ± 0.03# 0.24 ± 0.04*,# 0.23 ± 0.03*,#,
  1. Abbreviations: BW body weight, HW heart weight, HW/BW heart weight to body weight ratio, LHW left heart weight, LVAWTh left ventricular anterior wall thickness.
  2. Values are mean ± s.e.m.
  3. *P < 0.05 vs. sham; #P < 0.05 vs. model; P < 0.05 vs. captopril.