|
Groups & Dose
|
Mean paw volume ± SEM (mL) (% Inhibition
a
)
|
|---|
|
0 hr
|
2 hr
|
4 hr
|
6 hr
|
|---|
|
Vehicle control (0.5% CMC) 0 mg/kg b.w.
|
1.35 ± 0.03
|
1.46 ± 0.03
|
1.50 ± 0.03
|
1.42 ± 0.04
|
|
Standard (diclofenac)
|
1.38 ± 0.04
|
1.50 ± 0.02
|
1.37 ± 0.03*
|
1.41 ± 0.04
|
|
10 mg/kg b.w.
|
(-2.22%)
|
(-2.74%)
|
(8.66%)
|
(0.70%)
|
|
Polygonum minus aqueous extract
|
1.33 ± 0.02
|
1.47 ± 0.04
|
1.32 ± 0.03**
|
1.40 ± 0.05
|
|
100 mg/kg b.w.
|
(1.48%)
|
(-0.68%)
|
(12.00%)
|
(1.41%)
|
|
Polygonum minus aqueous extract
|
1.38 ± 0.03
|
1.42 ± 0.02
|
1.34 ± 0.02**
|
1.35 ± 0.04
|
|
300 mg/kg b.w.
|
(-2.22%)
|
(2.74%)
|
(10.67%)
|
(4.93%)
|
- Values are expressed as mean ± SEM, n = 8 (4Male + 4Female); (-) = No inhibition.
-
aInhibition is reported as a percentage compared to control.
- *Vehicle control vs standard (p < 0.05).
- **Vehicle control vs Polygonum minus (100 mg/kg) / Polygonum minus (300 mg/kg) (p < 0.01).
