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Table 2 Effect of Polygonum minus extract on paw volume and percentage inhibition in carrageenan induced paw edema

From: Anti-inflammatory effects of Polygonum minus (Huds) extract (Lineminus™) in in-vitro enzyme assays and carrageenan induced paw edema

Groups & Dose Mean paw volume ± SEM (mL) (% Inhibition a )
0 hr 2 hr 4 hr 6 hr
Vehicle control (0.5% CMC) 0 mg/kg b.w. 1.35 ± 0.03 1.46 ± 0.03 1.50 ± 0.03 1.42 ± 0.04
Standard (diclofenac) 1.38 ± 0.04 1.50 ± 0.02 1.37 ± 0.03* 1.41 ± 0.04
10 mg/kg b.w. (-2.22%) (-2.74%) (8.66%) (0.70%)
Polygonum minus aqueous extract 1.33 ± 0.02 1.47 ± 0.04 1.32 ± 0.03** 1.40 ± 0.05
100 mg/kg b.w. (1.48%) (-0.68%) (12.00%) (1.41%)
Polygonum minus aqueous extract 1.38 ± 0.03 1.42 ± 0.02 1.34 ± 0.02** 1.35 ± 0.04
300 mg/kg b.w. (-2.22%) (2.74%) (10.67%) (4.93%)
  1. Values are expressed as mean ± SEM, n = 8 (4Male + 4Female); (-) = No inhibition.
  2. aInhibition is reported as a percentage compared to control.
  3. *Vehicle control vs standard (p < 0.05).
  4. **Vehicle control vs Polygonum minus (100 mg/kg) / Polygonum minus (300 mg/kg) (p < 0.01).