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Table 6 Effect of methanolic extract of C. nurvala leaf on Involvement of ATP-sensitive K + channel pathway

From: Evaluation of antinociceptive effect of methanolic extract of leaves of Crataeva nurvala Buch.-Ham.

Treatment

Dose (mg/kg)

Responses

  

Number of writhing (Mean ± SEM)

% Inhibition

Control

0.1 ml/mouse

73.90 ± 1.61

-

Diclofenac sodium

10

19.90 ± 0.53*

73.07

MECN

50

54.70 ± 1.83*

25.98

MECN

100

29.90 ± 0.66*

59.54

MECN

200

18.30 ± 1.25*

75.24

Glib

10

75.1 ± 2.01

−1.62

Glib + Diclofenac-sodium

10 + 10

36.20 ± 1.77a

51.05

Glib + MECN

10 + 50

50.00 ± 1.53

32.34

Glib + MECN

10 + 100

28.00 ± 2.13

62.11

Glib + MECN

10 + 200

20.00 ± 1.34

72.94

  1. Each value is presented as the Mean ± SEM (n = 5). MECN = Methanolic extract of. Crataeva nurvala leaves; Glib = Glibenclemide.
  2. *p < 0.001 compared with the control group (Dunnett’s test).
  3. a p < 0.001 compared with the Diclofenac sodium treated group (Bonferroni’s test).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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