The effect of soyo-san extract on quantities of IL-1β immunostained nuclei expression in the hippocampal regions of the experimental groups after forced swimming test. (A) The results of IL-1β-reactivity were analyzed by performing separate one-way ANOVA of neurons among the groups. Each value represents the mean ± S.E.M. ***P < 0.001 compared to OVX+ST. ##P < 0.01 compared to non-op. B-I: Representative photographs of IL-1β-immunostained brain sections. Scale bars, 200 um. non-op (B,F), OVX+ST (C,G), SOY 100 (D,H) and SOY 400 (E, I).