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Table 8 Effects of oils of C. copticum , T. vulgaris and thymol on biofilm formation in drug-resistant and -sensitive strains of C. albicans

From: Sub-MICs of Carum copticum and Thymus vulgaris influence virulence factors and biofilm formation in Candida spp

Test agents

Biofilm formation

C. albicans 04

C. albicans SC5314

0.5 × MIC

0.25 × MIC

0.5 × MIC

0.25 × MIC

Essential oils

    

C. copticum

25.32 ± 2.68

40.08 ± 3.69

28.50 ± 2.41

42.92 ± 2.48

T. vulgaris

07.49 ± 0.98

11.70 ± 1.91

14.72 ± 1.05

25.04 ± 2.54

Thymol

07.59 ± 1.69

08.34 ± 1.93

06.90 ± 1.34

07.85 ± 1.18

Antifungal drug

    

Fluconazole

48.16 ± 0.97

67.61 ± 1.39

48.63 ± 2.24

65.34 ± 3.32