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Table 5 Viability assays of strains of Candida spp. e × posed to sub-inhibitory concentrations of oils of C. copticum , T. vulgaris and thymol

From: Sub-MICs of Carum copticum and Thymus vulgaris influence virulence factors and biofilm formation in Candida spp

Test agents (sub-MICs)

Cell viability assay (log cfu.mL−1at 105dilution)

C. albicans 04

C. albicans 05

C. albicans 07

C. albicans 09

C. albicans 16

C. albicans MTCC183

C. albicans SC5314

C. tropicalis 01

Untreated

8.14 ± 0.02

8.04 ± 0.01

8.12 ± 0.03

8.25 ± 0.01

8.02 ± 0.04

8.19 ± 0.01

8.45 ± 0.03

8.07 ± 0.04

Essential oils

        

C. copticum

        

0.25 × MIC

7.16 ± 0.04

7.29 ± 0.07

7.34 ± 0.03

7.26 ± 0.04

7.40 ± 0.06

7.38 ± 0.05

7.60 ± 0.02

7.41 ± 0.04

0.5 × MIC

6.10 ± 0.03

6.39 ± 0.05

6.46 ± 0.04

6.24 ± 0.02

6.35 ± 0.03

6.44 ± 0.04

7.17 ± 0.01

6.98 ± 0.05

T. vulgaris

        

0.25 × MIC

7.09 ± 0.03

7.24 ± 0.06

7.14 ± 0.05

7.19 ± 0.05

7.37 ± 0.04

7.32 ± 0.05

7.71 ± 0.04

7.52 ± 0.02

0.5 × MIC

6.43 ± 0.06

6.41 ± 0.05

6.39 ± 0.07

6.19 ± 0.04

6.27 ± 0.06

6.44 ± 0.07

7.02 ± 0.04

6.71 ± 0.06

Thymol

        

0.25 × MIC

7.11 ± 0.02

7.16 ± 0.04

7.23 ± 0.06

7.22 ± 0.03

7.24 ± 0.06

7.26 ± 0.05

7.44 ± 0.07

7.29 ± 0.03

0.5 × MIC

6.23 ± 0.04

6.54 ± 0.03

6.44 ± 0.03

6.33 ± 0.06

6.23 ± 0.05

6.33 ± 0.05

7.08 ± 0.07

6.45 ± 0.05

Antifungal drug

        

Fluconazole

        

0.25 × MIC

7.08 ± 0.03

7.11 ± 0.06

7.23 ± 0.05

7.16 ± 0.05

7.22 ± 0.04

7.31 ± 0.04

7.14 ± 0.06

7.31 ± 0.05

0.5 × MIC

6.18 ± 0.04

6.45 ± 0.06

6.44 ± 0.05

6.27 ± 0.04

6.15 ± 0.06

6.04 ± 0.05

7.23 ± 0.04

6.88 ± 0.06

  1. Within the columns, untreated means followed by treated means are non-significantly different according to Duncan’s multiple range tests (P < 0.05).